TRIM3 polyclonal antibody
产品名称: TRIM3 polyclonal antibody
英文名称: TRIM3 polyclonal antibody
产品编号: PAB6346
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
                    - 联系人 :
 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Goat polyclonal antibody raised against synthetic peptide of TRIM3.
 
- Immunogen:
 - A synthetic peptide corresponding to human TRIM3.
 
- Sequence:
 - AKREDSPGPEVQP-C
 
- Host:
 - Goat
 
- Theoretical MW (kDa):
 - 80.8
 
- Reactivity:
 - Mouse
 
- Specificity:
 - This antibody is expected to recognize both variants (NP_006449.2, NP_150594.2,) represent the same protein. This antibody is expected to recognize all three human isoforms of this protein.
 
- Form:
 - Liquid
 
- Purification:
 - Antigen affinity purification
 
- Concentration:
 - 0.5 mg/mL
 
- Storage Buffer:
 - In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
 
- Storage Instruction:
 - Store at -20°C.
Aliquot to avoid repeated freezing and thawing. 
- Quality Control Testing:
 - Antibody Reactive Against Synthetic Peptide.
 
- Recommend Usage:
 - ELISA (1:64000)
Western Blot (0.1-1 ug/mL)
The optimal working dilution should be determined by the end user. 
- Note:
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 
- Publication Reference
 
- 1.
 - Cloning and characterization of a gene (RNF22) encoding a novel brain expressed ring finger protein (BERP) that maps to human chromosome 11p15.5.
El-Husseini AE, Fretier P, Vincent SR.Genomics. 2001 Feb 1;71(3):363-7. 
- Applications
 
- Western Blot (Tissue lysate)
 
- TRIM3 polyclonal antibody (Cat # PAB6346) staining (0.05 ug/mL) of mouse brain lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
 
- Entrez GeneID:
 - 10612
 
- Protein Accession#:
 - NP_006449.2;NP_150594.2
 
- Gene Name:
 - TRIM3
 
- Gene Alias:
 - BERP,FLJ16135,HAC1,RNF22,RNF97
 
- Gene Description:
 - tripartite motif-containing 3
 
- Omim ID:
 - 605493
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq
 
- Other Designations:
 - brain expressed ring finger,ring finger protein 22,tripartite motif protein TRIM3
 

